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Pemphigus vulgaris Print E-mail
Pemphigus Vulgaris is the most common form of any of the pemphigus disorders. It occurs when antibodies attack Desmoglein 3, a protein that keeps cells bound together. Thus cells simply fall apart, causing skin to slough off. Although pemphigus vulgaris may occur at any age, it is quite rare in children, and most common in the middle aged and elderly. Sores often originate in the mouth, making eating difficult and uncomfortable . Pemphigus vulgaris often affects people between the ages of 40-60.
 
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